PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.

PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells.

PAX transcription factors play an important role during development and carcinogenesis. In this study, we investigated PAX2 protein levels in melanocytes and melanoma cells by Western Blot and immunofluorescence analysis and characterized the role of PAX2 in the pathogenesis of melanoma. In vitro we...

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Bibliographic Details
Main Authors: Sophia Boyoung Lee, Kai Doberstein, Peter Baumgarten, Anja Wieland, Christopher Ungerer, Claudia Bürger, Katja Hardt, Wolf-Henning Boehncke, Josef Pfeilschifter, Daniela Mihic-Probst, Michel Mittelbronn, Paul Gutwein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3158060?pdf=render

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http://europepmc.org/articles/PMC3158060?pdf=render

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