Delayed Onset Muscle Soreness (DOMS): The Repeated Bout Effect and Chemotherapy-Induced Axonopathy May Help Explain the Dying-Back Mechanism in Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases

Delayed onset muscle soreness (DOMS) is hypothesized to be caused by glutamate excitotoxicity-induced acute compression axonopathy of the sensory afferents in the muscle spindle. Degeneration of the same sensory afferents is implicated in the disease onset and progression of amyotrophic lateral scle...

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Bibliographic Details
Main Author: Balázs Sonkodi
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/11/1/108