A novel Bayesian method for detection of APOBEC3-mediated hypermutation and its application to zoonotic transmission of simian foamy viruses.

Simian Foamy Virus (SFV) can be transmitted from non-human primates (NHP) to humans. However, there are no documented cases of human to human transmission, and significant differences exist between infection in NHP and human hosts. The mechanism for these between-host differences is not completely u...

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Bibliographic Details
Main Authors: Frederick A Matsen, Christopher T Small, Khanh Soliven, Gregory A Engel, Mostafa M Feeroz, Xiaoxing Wang, Karen L Craig, M Kamrul Hasan, Michael Emerman, Maxine L Linial, Lisa Jones-Engel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-02-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586139/pdf/?tool=EBI