Purinergic signaling to terminate TLR responses in macrophages

Macrophages undergo profound physiological alterations when they encounter pathogen associated molecular patterns (PAMPs). These alterations can result in the elaboration of cytokines and mediators that promote immune responses and contribute to the clearance of pathogens. These innate immune resp...

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Bibliographic Details
Main Authors: Kajal eHamidzadeh, David M Mosser
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Immunology
Subjects:
ATP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00074/full