Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis.

Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis.

Antimicrobial peptides (AMPs) are strongly expressed in lesional skin in psoriasis and play an important role as proinflammatory "alarmins" in this chronic skin disease. Vitamin D analogs like calcipotriol have antipsoriatic effects and might mediate this effect by changing AMP expression....

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Bibliographic Details
Main Authors: Mark Peric, Sarah Koglin, Yvonne Dombrowski, Katrin Gross, Eva Bradac, Amanda Büchau, Andreas Steinmeyer, Ulrich Zügel, Thomas Ruzicka, Jürgen Schauber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2709447?pdf=render

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http://europepmc.org/articles/PMC2709447?pdf=render

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