Elevated OPRD1 promoter methylation in Alzheimer's disease patients.

Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder in the elderly. OPRD1 encodes the delta opioid receptor, a member of the opioid family of G-protein-coupled receptors. In the current study, we compare the DNA methylati...

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Bibliographic Details
Main Authors: Huihui Ji, Yunliang Wang, Guili Liu, Lan Chang, Zhongming Chen, Dongsheng Zhou, Xuting Xu, Wei Cui, Qingxiao Hong, Liting Jiang, Jinfeng Li, Xiaohui Zhou, Ying Li, Zhiping Guo, Qin Zha, Yanfang Niu, Qiuyan Weng, Shiwei Duan, Qinwen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5333823?pdf=render