Structural basis of the dynamic human CEACAM1 monomer-dimer equilibrium
To understand how hCEACAM1 transitions between monomeric and dimeric states that are required for its activity, Gandhi et al. investigate hCEACAM1 homodimeric, monomeric, and transition states and their behavior in solution. This study suggests the flexibility of the GFCC’ face and its role in gover...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-01871-2 |