The CD14 rs2569190 TT Genotype Is Associated with an Improved 30-Day Survival in Patients with Sepsis: A Prospective Observational Cohort Study.

According to previous investigations, CD14 is suggested to play a pivotal role in initiating and perpetuating the pro-inflammatory response during sepsis. A functional polymorphism within the CD14 gene, rs2569190, has been shown to impact the pro-inflammatory response upon stimulation with lipopolys...

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Bibliographic Details
Main Authors: Ashham Mansur, Benjamin Liese, Maximilian Steinau, Michael Ghadimi, Ingo Bergmann, Mladen Tzvetkov, Aron Frederik Popov, Tim Beissbarth, Martin Bauer, José Hinz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4447461?pdf=render