Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails

We have previously introduced the use of permeabilized fission yeast cells (enzyme bags) that recombinantly express full-length CYPs for drug metabolism studies. Such enzyme bags are cells with pores that function as enzymes in situ. They can easily be prepared without a need for ultracentrifugation...

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Bibliographic Details
Main Authors: Sangeeta Shrestha Sharma, Shishir Sharma, Matthias Bureik
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Journal of Pharmaceutical Analysis
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177920301696