Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails
We have previously introduced the use of permeabilized fission yeast cells (enzyme bags) that recombinantly express full-length CYPs for drug metabolism studies. Such enzyme bags are cells with pores that function as enzymes in situ. They can easily be prepared without a need for ultracentrifugation...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-06-01
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Series: | Journal of Pharmaceutical Analysis |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177920301696 |