COMPARISON OF BLADDER CANCER CELLS APOPTOSIS INDUCED BY METFORMIN, CISPLATIN, AND COMBINATION OF METFORMIN-CISPLATIN: IN VITRO STUDY

Objective: To evaluate the effect of metformin, cisplatin, and their combination on apoptosis of bladder cancer cells. Material & Methods: Urothelial cell lines 5637 were cultured until 80% confluence. Cells were exposed to metformin and cisplatin at certain doses for 24 and 48 hours. Cytotoxic...

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Bibliographic Details
Main Authors: Arifai Lumbangaol, Lukman Hakim, Doddy M Soebadi, Tarmono Djojodimedjo
Format: Article
Language:English
Published: IKATAN AHLI UROLOGI INDONESIA 2020-01-01
Series:Jurnal Urologi Indonesia
Subjects:
Online Access:http://juri.urologi.or.id/juri/article/view/600