Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology

Staphylococcus aureus necrotizing pneumonia is recognized as a toxin-mediated disease, yet the tissue-destructive events remain elusive, partly as a result of lack of mechanistic studies in human lung tissue. In this study, a three-dimensional (3D) tissue model composed of human lung epithelial cell...

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Bibliographic Details
Main Authors: Srikanth Mairpady Shambat, Puran Chen, Anh Thu Nguyen Hoang, Helena Bergsten, Francois Vandenesch, Nikolai Siemens, Gerard Lina, Ian R. Monk, Timothy J. Foster, Gayathri Arakere, Mattias Svensson, Anna Norrby-Teglund
Format: Article
Language:English
Published: The Company of Biologists 2015-11-01
Series:Disease Models & Mechanisms
Subjects:
Staphylococcus aureus
Pneumonia
3D lung tissue model
Online Access:http://dmm.biologists.org/content/8/11/1413

Internet

http://dmm.biologists.org/content/8/11/1413

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