Controlled 3D co-culture of beta cells and endothelial cells in a micropatterned collagen sheet for reproducible construction of an improved pancreatic pseudo-tissue

The co-culture of beta cells and endothelial cells in constructing a pancreatic pseudo-tissue can provide a functional advancement for in vitro diabetic-related drug testing and biological studies or in vivo transplantation. In order to mimic the pancreatic tissue more similar to in vivo, it is nece...

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Bibliographic Details
Main Authors: Haewon Seo, Jaejung Son, Je-Kyun Park
Format: Article
Language:English
Published: AIP Publishing LLC 2020-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0023873