Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates.

Countless studies monitor the growth rate of microbial populations as a measure of fitness. However, an enormous gap separates growth-rate differences measurable in the laboratory from those that natural selection can distinguish efficiently. Taking advantage of the recent discovery that transcript...

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Bibliographic Details
Main Authors: Kerry A Geiler-Samerotte, Tatsunori Hashimoto, Michael F Dion, Bogdan A Budnik, Edoardo M Airoldi, D Allan Drummond
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3783400?pdf=render