Copper-catalysed regioselective sulfenylation of indoles with sodium sulfinates

A copper-catalysed sulfenylation of indoles with sodium sulfinates that affords 3-sulfenylindoles in good-to-excellent yields in N,N-dimethyl formamide (DMF) is described. In the process, DMF serves not only as a solvent but also as a reductant. This transformation is easy to carry out and has mild...

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Bibliographic Details
Main Authors: Xiaojun Luo, Qiang Liu, Hongxia Zhu, Huoji Chen
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180170