The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity

Abstract Chemotherapy-induced peripheral neuropathic pain (CIPN) is a common and severe debilitating side effect of many widely used cytostatics. However, there is no approved pharmacological treatment for CIPN available. Among other substances, oxaliplatin causes CIPN in up to 80% of treated patien...

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Bibliographic Details
Main Authors: Stephan W. Hohmann, Carlo Angioni, Sorin Tunaru, Seungkyu Lee, Clifford J. Woolf, Stefan Offermanns, Gerd Geisslinger, Klaus Scholich, Marco Sisignano
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00591-0

Internet

https://doi.org/10.1038/s41598-017-00591-0

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