Targeting Cell Adhesion Molecules via Carbonate Apatite-Mediated Delivery of Specific siRNAs to Breast Cancer Cells In Vitro and In Vivo

Targeting Cell Adhesion Molecules via Carbonate Apatite-Mediated Delivery of Specific siRNAs to Breast Cancer Cells In Vitro and In Vivo

While several treatment strategies are applied to cure breast cancer, it still remains one of the leading causes of female deaths worldwide. Since chemotherapeutic drugs have severe side effects and are responsible for development of drug resistance in cancer cells, gene therapy is now considered as...

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Bibliographic Details
Main Authors: Maeirah Afzal Ashaie, Rowshan Ara Islam, Nur Izyani Kamaruzman, Nabilah Ibnat, Kyi Kyi Tha, Ezharul Hoque Chowdhury
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Pharmaceutics
Subjects:
breast cancer
siRNA
gene silencing
nanoparticle
carbonate apatite
α-catenin
β-catenin
talin-1
vinculin
paxillin and actinin-1
Online Access:https://www.mdpi.com/1999-4923/11/7/309

Internet

https://www.mdpi.com/1999-4923/11/7/309

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