A Protective and Pathogenic Role for Complement During Acute Toxoplasma gondii Infection

A Protective and Pathogenic Role for Complement During Acute Toxoplasma gondii Infection

The infection competence of the protozoan pathogen Toxoplasma gondii is critically dependent on the parasite’s ability to inactivate the host complement system. Toxoplasma actively resists complement-mediated killing in non-immune serum by recruiting host-derived complement regulatory proteins C4BP...

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Bibliographic Details
Main Authors: Patricia M. Sikorski, Alessandra G. Commodaro, Michael E. Grigg
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
complement
Toxoplasma gondii
C4BP
factor H
regulation
immune evasion
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.634610/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.634610/full

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