Identification and validation of the mode of action of the chalcone anti-mycobacterial compounds

Objectives: The search for new TB drugs has become one of the great challenges for modern medicinal chemistry. An improvement in the outcomes of TB chemotherapy can be achieved by the development of new, shorter, cheap, safe and effective anti-TB regimens. Methods: Chalcones (1a-1o) were synthesized...

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Bibliographic Details
Main Authors: B. Anagani, J. Singh, J.P. Bassin, G.S. Besra, C. Benham, T.R.K. Reddy, J.A.G. Cox, M. Goyal
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:The Cell Surface
Subjects:
MIC
Online Access:http://www.sciencedirect.com/science/article/pii/S2468233020300086