Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation.

Intracellular modulation, extracellular disposal and serum increase of MiR-150 mark lymphocyte activation.

Activated lymphocytes release nano-sized vesicles (exosomes) containing microRNAs that can be monitored in the bloodstream. We asked whether elicitation of immune responses is followed by release of lymphocyte-specific microRNAs. We found that, upon activation in vitro, human and mouse lymphocytes d...

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Bibliographic Details
Main Authors: Paola de Candia, Anna Torri, Tatiana Gorletta, Maya Fedeli, Elisabetta Bulgheroni, Cristina Cheroni, Francesco Marabita, Mariacristina Crosti, Monica Moro, Elena Pariani, Luisa Romanò, Susanna Esposito, Fabio Mosca, Grazisa Rossetti, Riccardo L Rossi, Jens Geginat, Giulia Casorati, Paolo Dellabona, Massimiliano Pagani, Sergio Abrignani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805464?pdf=render

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http://europepmc.org/articles/PMC3805464?pdf=render

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