Immune microenvironment changes induced by neoadjuvant chemotherapy in triple-negative breast cancers: the MIMOSA-1 study

Immune microenvironment changes induced by neoadjuvant chemotherapy in triple-negative breast cancers: the MIMOSA-1 study

Abstract Background The immune microenvironment (IME) of triple-negative breast cancers (TNBCs) and its modulation by neoadjuvant chemotherapy (NACT) remain to be fully characterized. Our current study aims to evaluate NACT-induced IME changes and assess the prognostic value of specific immune bioma...

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Bibliographic Details
Main Authors: Victor Sarradin, Amélie Lusque, Thomas Filleron, Florence Dalenc, Camille Franchet
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Breast Cancer Research
Subjects:
Triple-negative breast cancer
Neoadjuvant chemotherapy
Immune microenvironment
Tumor-infiltrating lymphocytes
TILs
PD-L1
Online Access:https://doi.org/10.1186/s13058-021-01437-4

Internet

https://doi.org/10.1186/s13058-021-01437-4

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