Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients

Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients

Initially underestimated as platelet dust, extracellular vesicles are continuously gaining interest in the field of inflammation. Various studies addressing inflammatory diseases have shown that microvesicles (MVs) originating from different cell types are systemic transport vehicles carrying distin...

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Bibliographic Details
Main Authors: Ebru Karasu, Julia Demmelmaier, Stephanie Kellermann, Karlheinz Holzmann, Jörg Köhl, Christoph Q. Schmidt, Miriam Kalbitz, Florian Gebhard, Markus S. Huber-Lang, Rebecca Halbgebauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
multiple trauma
microvesicle shedding
anaphylatoxin C5a
C5aR1
neutrophils
polymorphonuclear neutrophils (PMNs)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01789/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01789/full

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