Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes.

A number of machine learning-based predictors have been developed for identifying immunogenic T-cell epitopes based on major histocompatibility complex (MHC) class I and II binding affinities. Rationally selecting the most appropriate tool has been complicated by the evolving training data and machi...

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Bibliographic Details
Main Authors: Weilong Zhao, Xinwei Sher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC6224037?pdf=render