Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROS.

Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROS.

Heme is a ubiquitous molecule that has a number of physiological roles. The toxic effects of this molecule have been demonstrated in various models, based on both its pro-oxidant nature and through a detergent mechanism. It is estimated that about 10 mM of heme is released during blood digestion in...

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Bibliographic Details
Main Authors: Natália Pereira de Almeida Nogueira, Cintia Fernandes de Souza, Francis Monique de Souza Saraiva, Pedro Elias Sultano, Sergio Ranto Dalmau, Roberta Eitler Bruno, Renata de Lima Sales Gonçalves, Gustavo Augusto Travassos Laranja, Luís Henrique Monteiro Leal, Marsen Garcia Pinto Coelho, Claudio A Masuda, Marcus F Oliveira, Marcia Cristina Paes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22022475/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22022475/?tool=EBI

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