Ligand activation of the prokaryotic pentameric ligand-gated ion channel ELIC.

While the pentameric ligand-gated ion channel ELIC has recently provided first insight into the architecture of the family at high resolution, its detailed investigation was so far prevented by the fact that activating ligands were unknown. Here we describe a study on the functional characterization...

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Bibliographic Details
Main Authors: Iwan Zimmermann, Raimund Dutzler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3119659?pdf=render