Fak silencing impairs osteogenic differentiation of bone mesenchymal stem cells induced by uniaxial mechanical stretch

Background/purpose: Mechanical stretch plays a key role in promoting proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs) in distraction osteogenesis (DO). A better understanding of how the extracellular biomechanical stimulation is transferred to intracellular signal expr...

Full description

Bibliographic Details
Main Authors: Pei Hu, Xiaowen Zhu, Chuang Zhao, Jing Hu, En Luo, Bin Ye
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Journal of Dental Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1991790218310468