Distinct DNA Methylation Profiles in Ovarian Tumors: Opportunities for Novel Biomarkers

Distinct DNA Methylation Profiles in Ovarian Tumors: Opportunities for Novel Biomarkers

Aberrant methylation of multiple promoter CpG islands could be related to the biology of ovarian tumors and its determination could help to improve treatment strategies. DNA methylation profiling was performed using the Methylation Ligation-dependent Macroarray (MLM), an array-based analysis. Promot...

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Bibliographic Details
Main Authors: Lorena Losi, Sergio Fonda, Sara Saponaro, Sonia T. Chelbi, Cesare Lancellotti, Gaia Gozzi, Loredana Alberti, Luca Fabbiani, Laura Botticelli, Jean Benhattar
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian carcinoma
DNA methylation profiling
Wnt pathway
DNA damage repair system
TERT
MGMT
BRCA1
MLH1
OSMR
ESR1
FOXL2
Online Access:http://www.mdpi.com/1422-0067/19/6/1559

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http://www.mdpi.com/1422-0067/19/6/1559

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