Effects of excitotoxicity in the hypothalamus in transgenic mouse models of Huntington disease
Huntington disease (HD) is a fatal neurodegenerative movement disorder caused by an expanded CAG repeat in the huntingtin gene (HTT). The mutant huntingtin protein is ubiquitously expressed, but only certain brain regions are affected. The hypothalamus has emerged as an important area of pathology w...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-08-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844021019113 |