Expression of cytochrome P450 2C and 3A in female rat liver after long-term administration of gonadoliberin analogs

Expression of cytochrome P450 2C and 3A in female rat liver after long-term administration of gonadoliberin analogs

Objectives: Gonadoliberin (GnRH) analogs may be expected to indirectly modify growth hormone (GH) total concentration and its 24-h secretion profile. As a consequence, changes in the levels of GH may modify the mechanism of sexdependent cytochromes P450 (CYP450) synthesis, including the expression o...

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Bibliographic Details
Main Authors: Rafał Skowronek, Piotr Czekaj, Aleksandra Suszka-Świtek, Ewa Czech, Anna Wiaderkiewicz, Danuta Plewka, Aleksandra Bryzek
Format: Article
Language:English
Published: Nofer Institute of Occupational Medicine 2016-04-01
Series:International Journal of Occupational Medicine and Environmental Health
Subjects:
CYP2C
CYP3A
liver-enriched transcription factors
growth hormone
dalarelin
cetrorelix
Online Access:http://ijomeh.eu/Expression-of-cytochrome-P450-2C-and-3A-in-female-rat-liver-after-long-term-administration-of-gonadoliberin-analogs,58557,0,2.html

Internet

http://ijomeh.eu/Expression-of-cytochrome-P450-2C-and-3A-in-female-rat-liver-after-long-term-administration-of-gonadoliberin-analogs,58557,0,2.html

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