Synthesis, chemo-informatics, and anticancer evaluation of fluorophenyl-isoxazole derivatives

The current study aimed to design and synthesize a novel series of fluorophenyl-isoxazole-carboxamide derivatives and evaluate their antiproliferative activities. Anticancer activities of the novel compounds were evaluated by MTS assay against four cancer cell lines, including liver (Hep3B, HepG2),...

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Bibliographic Details
Main Authors: Hawash Mohammed, Jaradat Nidal, Abualhasan Murad, Amer Johnny, Levent Serkan, Issa Shahd, Ibrahim Sameeha, Ayaseh Aseel, Shtayeh Tahrir, Mousa Ahmed
Format: Article
Language:English
Published: De Gruyter 2021-08-01
Series:Open Chemistry
Subjects:
Online Access:https://doi.org/10.1515/chem-2021-0078