Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).

Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant Creutzfeldt-Jakob disease (vCJD). Unlike scrapie and chronic wasting disease there is no cell culture model allowing the replication of proteina...

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Bibliographic Details
Main Authors: Dongseob Tark, Hyojin Kim, Michael H Neale, Minjeong Kim, Hyunjoo Sohn, Yoonhee Lee, Insoo Cho, Yiseok Joo, Otto Windl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4315440?pdf=render