Multiparticulate Systems of Ezetimibe Micellar System and Atorvastatin Solid Dispersion Efficacy of Low-Dose Ezetimibe/Atorvastatin on High-Fat Diet-Induced Hyperlipidemia and Hepatic Steatosis in Diabetic Rats

Multiparticulate Systems of Ezetimibe Micellar System and Atorvastatin Solid Dispersion Efficacy of Low-Dose Ezetimibe/Atorvastatin on High-Fat Diet-Induced Hyperlipidemia and Hepatic Steatosis in Diabetic Rats

The aim of this study was to develop multiparticulate systems with a combination of ezetimibe micellar systems and atorvastatin solid dispersions using croscarmellose as a hydrophilic vehicle and Kolliphor RH40 as a surfactant. The presence of a surfactant with low hydrophilic polymer ratios produce...

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Bibliographic Details
Main Authors: Carlos Torrado-Salmerón, Víctor Guarnizo-Herrero, Joana Henriques, Raquel Seiça, Cristina M. Sena, Santiago Torrado-Santiago
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceutics
Subjects:
ezetimibe
atorvastatin
solid dispersion
micellar system
hyperlipidemia
liver steatosis
Online Access:https://www.mdpi.com/1999-4923/13/3/421

Internet

https://www.mdpi.com/1999-4923/13/3/421

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