CircHIPK3/miR-381-3p axis modulates proliferation, migration, and glycolysis of lung cancer cells by regulating the AKT/mTOR signaling pathway

CircHIPK3/miR-381-3p axis modulates proliferation, migration, and glycolysis of lung cancer cells by regulating the AKT/mTOR signaling pathway

Lung cancer is a lethal malignancy. Plenty of circular RNAs (circRNAs) have been identified to be the vital regulators in lung cancer development. Here, we intended to clarify the functional role of circRNA HIPK3 (circHIPK3, also called hsa_circ_0021593) and its underlying mechanism of action. Quant...

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Bibliographic Details
Main Authors: Gu Feng, Zhang Junhan, Yan Lin, Li Dong
Format: Article
Language:English
Published: De Gruyter 2020-09-01
Series:Open Life Sciences
Subjects:
lung cancer
circhipk3
mir-381-3p
glycolysis
akt/mtor signaling pathway
Online Access:https://doi.org/10.1515/biol-2020-0070

Internet

https://doi.org/10.1515/biol-2020-0070

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