Involvement of BDNF/TrkB and ERK/CREB axes in nitroglycerin-induced rat migraine and effects of estrogen on these signals in the migraine
Migraine is a highly prevalent headache disorder, especially in women. Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin receptor kinases (TrkB), as well as extracellular signal-regulated kinase (ERK) and its downstream target c-AMP-responsive element binding protein (CREB) are s...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2017-01-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/6/1/8 |