Involvement of BDNF/TrkB and ERK/CREB axes in nitroglycerin-induced rat migraine and effects of estrogen on these signals in the migraine

Migraine is a highly prevalent headache disorder, especially in women. Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin receptor kinases (TrkB), as well as extracellular signal-regulated kinase (ERK) and its downstream target c-AMP-responsive element binding protein (CREB) are s...

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Bibliographic Details
Main Authors: Jiu-Qing Guo, Hui-Hui Deng, Xiao Bo, Xiao-Su Yang
Format: Article
Language:English
Published: The Company of Biologists 2017-01-01
Series:Biology Open
Subjects:
ERK
Online Access:http://bio.biologists.org/content/6/1/8