Activation and Regulation of the Pattern Recognition Receptors in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance

Activation and Regulation of the Pattern Recognition Receptors in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance

Obesity-associated chronic tissue inflammation is a key contributing factor to type 2 diabetes mellitus, and a number of studies have clearly demonstrated that the immune system and metabolism are highly integrated. Recent advances in deciphering the various immune cells and signaling networks that...

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Bibliographic Details
Main Authors: Kiyoshi Takatsu, Yasuharu Watanabe, Yoshinori Nagai
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:Nutrients
Subjects:
adipose tissue inflammation
cytokine
inflammasome
insulin resistance
metabolic syndrome
obesity
pattern recognition receptor
TLR
type 2 diabetes mellitus
Online Access:http://www.mdpi.com/2072-6643/5/9/3757

Internet

http://www.mdpi.com/2072-6643/5/9/3757

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