Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization

A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields. Further exploration of the molecular diversity of these compounds is demonstrated t...

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Bibliographic Details
Main Authors: Chunhui Dai, Bo Liang, Corey R. J. Stephenson
Format: Article
Language:English
Published: Beilstein-Institut 2012-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.8.111