The M1 muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice
Abstract Muscarinic acetylcholine receptors have been implicated as potential neuroprotective targets for glaucoma. We tested the hypothesis that the lack of a single muscarinic receptor subtype leads to age-dependent neuron reduction in the retinal ganglion cell layer. Mice with targeted disruption...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-41425-5 |