Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect

Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect

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C-type natriuretic peptide (CNP) is a pivotal enhancer of endochondral bone growth and is expected to be a therapeutic reagent for impaired skeletal growth. Although we showed that CNP stimulates bone growth as a local regulator in the growth plate via the autocrine/paracrine system, CNP is abundant...

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Bibliographic Details
Main Authors: Yohei Ueda, Keisho Hirota, Ichiro Yamauchi, Takuro Hakata, Takafumi Yamashita, Toshihito Fujii, Akihiro Yasoda, Nobuya Inagaki, Michael Bader
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529242/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529242/?tool=EBI

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