Effective MR Molecular Imaging of Triple Negative Breast Cancer With an EDB-Fibronectin-Specific Contrast Agent at Reduced Doses

Effective MR Molecular Imaging of Triple Negative Breast Cancer With an EDB-Fibronectin-Specific Contrast Agent at Reduced Doses

MR molecular imaging (MRMI) of abundant oncogenic biomarkers in tumor microenvironment has the potential to provide precision cancer imaging in high resolution. Extradomain-B fibronectin (EDB-FN) is an oncogenic extracellular matrix protein, highly expressed in aggressive triple negative breast canc...

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Bibliographic Details
Main Authors: Nadia R. Ayat, Amita Vaidya, Grace A. Yeung, Megan N. Buford, Ryan C. Hall, Peter L. Qiao, Xin Yu, Zheng-Rong Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
EDB-fibronectin
GBCAs
targeted MRI contrast agent
breast cancer
tumor microenvironment
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01351/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.01351/full

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