Cryoelectron tomography of HIV-1 envelope spikes: further evidence for tripod-like legs.

A detailed understanding of the morphology of the HIV-1 envelope (Env) spike is key to understanding viral pathogenesis and for informed vaccine design. We have previously presented a cryoelectron microscopic tomogram (cryoET) of the Env spikes on SIV virions. Several structural features were noted...

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Bibliographic Details
Main Authors: Ping Zhu, Hanspeter Winkler, Elena Chertova, Kenneth A Taylor, Kenneth H Roux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19008954/pdf/?tool=EBI