Mechanisms of action of sacubitril/valsartan on cardiac remodeling: a systems biology approach

Cardiology: Heart Failure Medication Reduces Heart Size The new wonder drug in heart failure management, Sacubitril/Valsartan, rejuvenates the heart by preventing its dilation. Using data from myocardial infarction and heart failure samples, we generated a mathematical model to better understand how...

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Bibliographic Details
Main Authors: Oriol Iborra-Egea, Carolina Gálvez-Montón, Santiago Roura, Isaac Perea-Gil, Cristina Prat-Vidal, Carolina Soler-Botija, Antoni Bayes-Genis
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-017-0013-4