Pharmacology of Antihistamines

This article reviews the molecular biology of the interaction of histamine with its H1-receptor and describes the concept that H1-antihistamines are not receptor antagonists but are inverse agonists i.e. they produce the opposite effect on the receptor to histamine. It then discourages the use of fi...

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Bibliographic Details
Main Authors: Diana S Church, MD, Martin K Church, PhD
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119304569