Prophylactic and therapeutic supplementation using fructo-oligosaccharide improves the intestinal homeostasis after mucositis induced by 5- fluorouracil

Prophylactic and therapeutic supplementation using fructo-oligosaccharide improves the intestinal homeostasis after mucositis induced by 5- fluorouracil

The beneficial effects of prebiotic, such as fructo-oligosaccharides (FOS), in intestinal inflammation have been demonstrated in several studies. Herein, we evaluate whether joint treatment with FOS, both before and during mucositis, had additional beneficial effects and investigated the mechanisms...

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Bibliographic Details
Main Authors: Paula Lopes Armond Carvalho, Maria Emília Rabelo Andrade, Luísa Martins Trindade, Paola Caroline Lacerda Leocádio, Jacqueline Isaura Alvarez-Leite, Diego Carlos dos Reis, Geovanni Dantas Cassali, Éricka Lorenna de Sales Souza e Melo, Flaviano dos Santos Martins, Simone Odília Antunes Fernandes, Maria do Carmo Gouveia Peluzio, Simone de Vasconcelos Generoso, Valbert Nascimento Cardoso
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Mucositis
Intestinal damage
Tight junction
Short-chain fatty acids
5-Fluorouracil
Fructo-oligosaccharide
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222031204X

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http://www.sciencedirect.com/science/article/pii/S075333222031204X

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