Bone and subcutaneous adipose tissue pharmacokinetics of vancomycin in total knee replacement patients

Background and purpose — The incidence of orthopedic methicillin-resistant Staphylococcus aureus (MRSA) infections is increasing. Vancomycin may therefore play an increasingly important role in orthopedic perioperative antimicrobial prophylaxis. Studies investigating perioperative bone and soft tiss...

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Bibliographic Details
Main Authors: Mats Bue, Mikkel Tøttrup, Pelle Hanberg, Otto Langhoff, Hanne Birke-Sørensen, Theis M Thillemann, Torben L Andersson, Kjeld Søballe
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Acta Orthopaedica
Online Access:http://dx.doi.org/10.1080/17453674.2017.1373497