Characterisation of the maternal response to chronic phase shifts during gestation in the rat: implications for fetal metabolic programming.

Disrupting maternal circadian rhythms through exposure to chronic phase shifts of the photoperiod has lifelong consequences for the metabolic homeostasis of the fetus, such that offspring develop increased adiposity, hyperinsulinaemia and poor glucose and insulin tolerance. In an attempt to determin...

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Bibliographic Details
Main Authors: Tamara J Varcoe, Michael J Boden, Athena Voultsios, Mark D Salkeld, Leewen Rattanatray, David J Kennaway
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3544759?pdf=render