Knockdown lncRNA CRNDE enhances temozolomide chemosensitivity by regulating autophagy in glioblastoma

Knockdown lncRNA CRNDE enhances temozolomide chemosensitivity by regulating autophagy in glioblastoma

Abstract Background The regulatory roles of long non-coding RNA (lncRNA) CRNDE in temozolomide (TMZ) chemoresistance to glioblastoma multiforme (GBM) are still poorly understood. Therefore, the function, characteristics, and possible mechanism of CRNDE in TMZ-induced chemoresistance to GBM were expl...

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Bibliographic Details
Main Authors: Zijin Zhao, Miaomiao Liu, Wenyong Long, Jian Yuan, Haoyu Li, Chi Zhang, Guodong Tang, Weixi Jiang, Xianrui Yuan, Minghua Wu, Qing Liu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
CRNDE
Glioblastoma multiforme
Temozolomide
Chemosensitivity
Autophagy
PI3K/Akt/mTOR
Online Access:https://doi.org/10.1186/s12935-021-02153-x

Internet

https://doi.org/10.1186/s12935-021-02153-x

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