Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice

Anti-thymocyte globulin (ATG) differentially depletes naïve and memory T cells and permits memory-type regulatory T cells in nonobese diabetic mice

<p>Abstract</p> <p>Background</p> <p>ATG has been employed to deplete T cells in several immune-mediated conditions. However, whether ATG administration affects naïve and memory T cell differently is largely unknown.</p> <p>The context and purpose of the stu...

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Bibliographic Details
Main Authors: Xia Chang-Qing, Chernatynskaya Anna V, Wasserfall Clive H, Wan Suigui, Looney Benjamin M, Eisenbeis Scott, Williams John, Clare-Salzler Michael J, Atkinson Mark A
Format: Article
Language:English
Published: BMC 2012-12-01
Series:BMC Immunology
Subjects:
Anti-thymocyte globulin
Naïve and memory T cells
Regulatory T cells
T helper cell
Autoimmune diabetes
Nonobese diabetic mouse
Online Access:http://www.biomedcentral.com/1471-2172/13/70

Internet

http://www.biomedcentral.com/1471-2172/13/70

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