7-oxygenated Derivatives of Dehydroepiandrosterone and Obesity

7-hydroxy/oxo derivatives of dehydroepiandrosterone are potential regulators of the local cortisol activity due to their competition in the cortisolcortisone balance mediated by 11β-hydroxysteroid dehydrogenase. 7-hydroxydehydroepiandrosterone is marketed as anti-obesity medication, though no clinic...

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Bibliographic Details
Main Authors: B. Sedláčková, L. Dušátková, H. Zamrazilová, P. Matucha, M. Bičíková, Luboslav Stárka
Format: Article
Language:English
Published: Karolinum Press 2012-01-01
Series:Prague Medical Report
Subjects:
Online Access:https://pmr.lf1.cuni.cz/113/2/0147/