Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

Systematic comparison of respiratory syncytial virus-induced memory B cell responses in two anatomical compartments

Here, the authors isolate over 800 RSV F-specific antibodies from paired nasopharyngeal tonsil and peripheral blood samples from four young children undergoing adenoidectomy and find that adenoid derived antibodies have overall higher binding affinities and neutralization potencies.

Bibliographic Details
Main Authors: Laila Shehata, Wendy F. Wieland-Alter, Daniel P. Maurer, Eunice Chen, Ruth I. Connor, Peter F. Wright, Laura M. Walker
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09085-1

Internet

https://doi.org/10.1038/s41467-019-09085-1

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