Effects of L-655,708 on expression changes of GABA, glutamate, and beta-endorphin induced by propofol anesthesia in rats

Anesthetics are considered to be one of the important inducing factors of postoperative cognitive dysfunction (POCD). The hippocampal region of the rat is one of the action sites of general anesthesia drugs. L 655,708, a reverse agonist of gamma aminobutyric acid (GABA) receptor, can significantly i...

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Bibliographic Details
Main Authors: Jin Wang, Xinyi Li, Huisheng Wu, Jianjuan Ke, Zongze Zhang, Yanlin Wang
Format: Article
Language:English
Published: SAGE Publishing 2018-08-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/2058739218796708